Tyler Morning Telegraph

New data on investigational therapy for thymidine kinase 2 deficiency presented at Muscular Dystrophy Association (MDA) 2025 Conference

Thymidine kinase 2 deficiency is an ultra-rare, life-threatening, genetic mitochondrial disease characterized by progressive and severe muscle weakness (myopathy), which can impact the ability to walk ...
Morningstar

Results published in Neurology highlight a 95% reduction in risk of death with pyrimidine nucleos(t)ide therapy in patients with thymidine kinase 2 deficiency (TK2d)

ATLANTA, Oct. 13, 2025 /PRNewswire/ -- UCB, a global biopharmaceutical company, today announced that Neurology has published results from a multicenter retrospective chart review study of ...
Phys.org

Rethinking how nucleoside supplementation speeds up DNA replication: It's not just about having enough

DNA, often called the blueprint of life, is built from four chemical building blocks known as deoxy-nucleoside triphosphates (dNTPs)—dATP, dTTP, dGTP, and dCTP. Cells constantly need these molecules ...
Nature

Molecular Conformation of Thymidine and a Comparison with some Electron Spin Resonance Results

THE determination of the structure of thymidine (C10 N2 O5 H14, Fig. 1) was undertaken as part of a series of structure determinations of nucleic acid components. Thymidine is the only nucleoside ...