Disorders like esophageal cancer and gastroesophageal reflux disease are difficult to treat without properly understanding the esophagus’s mechanical properties. The findings establish a baseline for ...

Presbyphagia refers to age-related changes in the oropharyngeal and esophageal swallowing of healthy adults. Sarcopenia is age-related loss of skeletal muscle mass, organization, and strength. Good ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

Treating diseases of the esophagus has long posed a frustrating challenge. Medications often pass through too quickly to work ...

Panel A shows the microscopic myoarchitecture of the circular and longitudinal muscle layers of the lower esophageal sphincter and stomach. The circular muscle fibers of the esophagus cross each other ...

Benign esophageal stricture is a noncancerous narrowing of the esophagus, often resulting from acid reflux that damages the esophageal lining over time. Symptoms include difficulty swallowing and ...

The upper esophageal sphincter (UES) closure muscles include the cervical esophagus, cricopharyngeus, and inferior pharyngeal constrictor, but primarily the cricopharyngeus. The main functions of UES ...

U.S. surgeons made the first successful esophageal reconstruction surgery through the use of FDA-approved skin tissue and stents. It took 11 years to make the full process of treatment and recovery, ...

Heartburn, accompanied by a burning sensation in the chest or throat when swallowing, may be a symptom of gastroesophageal reflux disease (GERD), a chronic condition in which stomach acid frequently ...

The esophagus is the tube that connects your mouth to your stomach. Barrett’s esophagus is a condition where the tissue in your lower esophagus becomes damaged. It starts to resemble the tissue in ...